|
|
|
MTA-12
: Opiates
The MTA-12
assay for opiates is designed to detect certain structurally
related compounds and to avoid detecting others, as shown
here. Of the 159
compounds tested,
only the following compounds exhibited cross reactivity
relative to the level of morphine (ng/mL) given
below:
|
|
Concentration
(Morphine - ng/mL)
|
|
Compounds
|
10
|
25
|
50
|
|
|
|
Atropine
|
32,500
|
>
50,000
|
>
50,000
|
|
Clomipramine
|
42,000
|
>
50,000
|
>
50,000
|
|
Codeine
|
4.6
|
13.7
|
32.0
|
|
Diacetylmorphine
|
13.1
|
27.5
|
63.0
|
|
Ethylmorphine
|
7.4
|
17.6
|
31.0
|
|
Hydrocodone
|
50
|
117
|
275
|
|
Hydromorphone
|
90
|
220
|
400
|
|
Meperidine
|
8,500
|
>10,000
|
>10,000
|
|
6-Mono-acetylmorphine
|
15
|
31
|
66
|
|
Morphine-3-B-D-glucuronide
|
10.7
|
36
|
86
|
|
Nalorphine
|
180
|
510
|
1140
|
|
Naloxone
|
42,000
|
>50,000
|
>50,000
|
|
Oxycodone
|
4,200
|
>
10,000
|
>
10,000
|
|
Oxymorphone
|
9,000
|
>
10,000
|
>
10,000
|
|
Thebaine
|
62
|
124
|
230
|
|
|