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MTA-12
: Barbiturates
The MTA assay for barbiturates is designed to detect certain structurally related compounds and to avoid detecting unrelated compounds, as shown here. Of the 164 compounds tested, only the following exhibited cross reactivity relative to the level of secobarbital (ng/mL) given below:
|
|
Concentration
(Secobarbital - ng/mL)
|
|
Compounds (ng/mL)
|
10
|
25
|
50
|
|
|
|
Amobarbital
|
175
|
375
|
800
|
|
Apobarbital
|
2,450
|
6,200
|
12,400
|
|
Butabarbital
|
380
|
880
|
1,550
|
|
Butalbital
|
780
|
1,830
|
3,600
|
|
Cyclopentobarbital
|
900
|
1,850
|
3,600
|
|
Diallybarbital
|
1,280
|
3,600
|
7,900
|
|
Morphine-3-beta-D-glucuronide
|
7,800
|
19,200
|
50,000
|
|
Pentobarbital
|
20
|
46
|
80
|
|
Phenobarbital
|
230
|
700
|
1,600
|
|
Talbutal
|
210
|
450
|
840
|
|
Thiopental
|
26
|
56
|
108
|
|